A Review of Three-dimensional Printing for Biomedical and Tissue Engineering Applications

M. Gundhavi Devi1, M. Amutheesan2, R. Govindhan3, B. Karthikeyan3, *
1 Centre for Bioscience and Nanoscience Research, Coimbatore, Tamil Nadu 641021, India
2 Department of Aeronautical Engineering, Hindustan Institute of Technology & Science, Padur, Chennai, Tamil Nadu 603103, India
3 Department of Chemistry, Annamalai University, Annamalai Nagar, Tamil Nadu 608 002, India

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© 2018 Devi et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: ( This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Chemistry, Annamalai University, Annamalai Nagar 608 002, Tamil Nadu, India; Tel: +91 9842491114; E-mail:



Various living organisms especially endangered species are affected due to the damaged body parts or organs. For organ replacement, finding the customized organs within the time by satisfying biomedical needs is the risk factor in the medicinal field.


The production of living parts based on the highly sensitive biomedical demands can be done by the integration of technical knowledge of Chemistry, Biology and Engineering. The integration of highly porous Biomedical CAD design and 3D bioprinting technique by maintaining the suitable environment for living cells can be especially done through well-known techniques: Stereolithography, Fused Deposition Modeling, Selective Laser Sintering and Inkjet printing are majorly discussed to get final products.


Among the various techniques, Biomedical CAD design and 3D printing techniques provide highly precise and interconnected 3D structure based on patient customized needs in a short period of time with less consumption of work.


In this review, biomedical development on complex design and highly interconnected production of 3D biomaterials through suitable printing technique are clearly reported.

Keywords: 3D bioprinting, 3D scaffold, Biomedical, Tissue engineering, Polymer, Rapid prototyping.