REVIEW ARTICLE


Application of Actinobacterial and Fungal Morphology on the Design of Operating Strategies in Bioprocess Development



T. Panda*, G.N. Rameshaiah
Biochemical Engineering Laboratory, MSB 140 A and MSB 235A, Department of Chemical Engineering Indian Institute of Technology, Madras, Chennai 600036, India


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Creative Commons License
© 2009 Panda and Rameshaiah

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Biochemical Engineering Laboratory, MSB 140 A and MSB 235A, Indian Institute of Technology, Madras, Chennai 600036, Índia; Tel: +91-9840708563 or +91-44-22574160; E-mail: panda@iitm.ac.in or pandaiitm@yahoo.co.in


Abstract

Various options in biotechnology have been exercised to produce industrially important metabolites from filamentous organisms. To select a suitable production strategy, the direct and indirect roles of morphological parameters in controlling bioprocess variables are observed. Some progress has been made in quantitation of morphology.Useful correlations have been reported in the literature in this avenue. Of course, some of the models, with proper modification, can be used to explain the morphological phenomena. This review is concerned with the application of morphological variables to correlate with bioprocess parameters for explaining optimal production strategy.