REVIEW ARTICLE


Open-Surface Digital Microfluidics



Jeong-Yeol Yoon*
Department of Agricultural and Biosystems Engineering, The University of Arizona, Tucson, Arizona 85721-0038, USA


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Creative Commons License
© 2008 Jeong-Yeol Yoon

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Agricultural and Biosystems Engineering, The University of Arizona, Tucson, Arizona 85721-0038, USA; E-mail: jyyoon@email.arizona.edu


Abstract

Open-surface digital microfluidics refers to droplet manipulations in an open surface. Different chemical/ biological reaction protocols can easily be demonstrated in the same device by reprogramming the order of droplet manipulations. While continuous-flow or liquid-plug microfluidics within microchannels have inherently limited programmability, there is no limit of reprogrammability in open-surface digital microfluidics. Three different mechanisms for droplet manipulations are addressed in this mini-review: electrowetting-on-dielectric, magnetofluidics and wire-guide manipulations. Brief theories of surface tension and work of adhesion are addressed. Potential applications are addressed as well as their complications.