Open-Surface Digital Microfluidics

Open-Surface Digital Microfluidics

Jeong-Yeol Yoon, * Open Modal
Authors Info & Affiliations
The Open Biotechnology Journal 16 Apr 2008 REVIEW ARTICLE DOI: 10.2174/1874070700802010094


Open-surface digital microfluidics refers to droplet manipulations in an open surface. Different chemical/ biological reaction protocols can easily be demonstrated in the same device by reprogramming the order of droplet manipulations. While continuous-flow or liquid-plug microfluidics within microchannels have inherently limited programmability, there is no limit of reprogrammability in open-surface digital microfluidics. Three different mechanisms for droplet manipulations are addressed in this mini-review: electrowetting-on-dielectric, magnetofluidics and wire-guide manipulations. Brief theories of surface tension and work of adhesion are addressed. Potential applications are addressed as well as their complications.