RESEARCH ARTICLE


The Uncertainty Assessment of Threonine Determination in Ginseng and Its Immune Activity



Jane yuxia Qin, Yan Chen, Dianshuai Gao, Ye Xiong*
Department of Neurobiology, Xuzhou Medical College, Jiangsu Province, 221994, China


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Creative Commons License
© 2014 Qin et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at Tongshan Road, Xuzhou, China. 221004; Tel: +8613814422945; E-mail: yuxiaemail@126.com


Abstract

Ginseng is one of famous herbs, which has many medical functions, such as neuroprotective effects, and anticancer function, because ginseng contains many active substances, and threonine is one important ingredient. In this study, to establish a mathematical model of uncertainty assessment for Threonine content in Ginseng by the amino acid assay, the sources of uncertainty in the measurement process were completely concerned, the main sources of uncertainty were fully analyzed, and evaluated and calculated. The results showed, for 0.2083g sample, the Threonine determination in Ginseng showed a good linear relationship. IN conclusion, this method developed in this study is suitable for the Uncertainty factors assessment of threonine measurement in Ginseng by amino acid assay. We also did animal test. To detect the immune activity of threonine in Ginseng, we detected the CD3+, CD19+ using FACS of mice after oral administration.

Keywords: Ginseng, threonine, Immune Activity, CD3+.